Workers Compensation Research

What Percentage of Workers Compensation Opioid Prescriptions Are High-Risk in Australia?

Groundbreaking Monash University research analyzing 30,000+ workers reveals 67% of Victorian workers comp opioid prescriptions are high-risk.

Luke McGrath, Pharmacist Updated November 2025 8 min read

67% of Victorian workers compensation opioid prescriptions are high-risk, with 22.8% of workers continuing use after one year. Monash University research analyzing 30,000+ workers found early high-risk prescribing doubles long-term dependency risk.

Research Note: This article references peer-reviewed research published by Monash University in CNS Drugs journal (Tefera et al., 2025). The study analyzed 30,590 Victorian workers with back/neck injuries from 2010-2019. Findings: 20.5% prescribed opioids within 3 months, 67.1% classified as high-risk prescriptions, 22.8% continued use after one year.

What's the Deal? Key Takeaways:

  • 67.1% of Victorian workers comp opioid prescriptions classified as high-risk
  • 20.5% of workers with back/neck injuries receive opioids within 3 months
  • 22.8% continue using opioids after one year
  • 2x risk: Early high-risk prescribing doubles chances of long-term dependency
  • Rural workers: Higher rates of high-risk prescribing and extended use
  • Data gap: Only 2 Australian states collect detailed medication prescribing data
  • 30,000+ workers: Largest study of opioid prescribing in Australian workers comp

How is high-risk opioid prescribing defined in workers compensation?

High-risk prescribing involves large volumes prescribed within the first three months, early prescription of long-acting opioids typically reserved for chronic conditions, or concurrent prescription of other high-risk medicines alongside opioids. The Monash University study used these three criteria to identify 67.1% of Victorian workers compensation opioid prescriptions as high-risk.

Three High-Risk Criteria

1. Large Early Volumes: Substantial quantities of opioid medications prescribed within the first three months often lead to dependency and extended utilization periods.

2. Early Long-Acting Opioids: Long-acting formulations prescribed early in treatment are associated with higher dependency risks when used for acute injuries.

3. Concurrent High-Risk Medications: Multiple high-risk medicines prescribed simultaneously increase risks of polypharmacy and dangerous drug interactions.

What did the Monash University study find?

The Monash University research analyzed 30,000+ Victorian workers with back and neck injuries between 2010-2019, finding 20.5% received opioids within 3 months. Of these prescriptions, 67.1% were classified as high-risk, and 22.8% of workers continued using opioids after one year. The study represents the most comprehensive analysis of opioid prescribing in Australian workers compensation to date.

Study Statistics

  • 30,000+ Workers Studied (2010-2019)
  • 6,278 Received Opioids (20.5%)
  • 67.1% High-Risk Prescriptions
  • 22.8% Long-Term Use After 1 Year

The research focused on back and neck injuries because these represent the most common workplace injuries requiring extended medical treatment and are frequently associated with chronic pain management challenges.

How does geography affect opioid prescribing rates?

Rural workers face significantly higher rates of high-risk opioid prescribing and long-term use compared to urban workers. The Monash study identified geographic disparities driven by limited access to alternative pain management, prescribing practice variations, and healthcare provider availability in rural and remote areas.

Workers in economically challenged locations demonstrated consistently higher rates of high-risk opioid prescribing, suggesting that geographic location significantly influences both initial prescribing decisions and long-term medication dependency risks.

Implications for Claims Managers

Targeted interventions addressing rural prescribing practices could significantly impact inappropriate opioid utilization. Rural-specific strategies might include telemedicine consultations, specialist pain management services, and enhanced prescriber education programs.

How do opioids impact return-to-work outcomes?

Workers using opioids early in their claims or for extended periods show longer time off work and worse health outcomes. Rather than facilitating faster return to work, the research suggests opioid therapy may actually impede recovery and extend disability periods, creating cycles where pain management perpetuates the problems it aims to solve.

Extended Disability Periods

Opioid users show longer time off work, generating substantial wage replacement costs and reduced return-to-work likelihood.

Functional Impairment

Medications cause cognitive effects, motor coordination problems, and reduced physical capacity interfering with rehabilitation.

Psychological Complications

Extended use contributes to depression, anxiety, and reduced self-efficacy affecting recovery motivation.

Which Australian states collect medication prescribing data?

Victoria is one of only two states in Australia that collect detailed information on medicines being prescribed through workers compensation systems. Most other jurisdictions cannot identify high-risk patterns, monitor trends, implement targeted interventions, measure effectiveness of policy changes, or benchmark prescribing practices against evidence-based standards.

The National Data Gap

If prescribing patterns observed in Victoria occur in other states and territories, potentially thousands of workers across Australia may be receiving high-risk opioid prescriptions funded by workers compensation systems. This represents a significant public health and financial risk that could be addressed through improved data collection capabilities.

The data gap also prevents identification of best practices, cross-jurisdictional learning, and development of national standards for medication management in workers compensation systems.

What is the financial cost of high-risk opioid prescribing?

High-risk prescribing creates massive indirect costs through extended disability periods, ongoing wage replacement, additional medical interventions, and intensive vocational rehabilitation - far exceeding direct medication costs. The 22.8% rate of workers continuing after one year represents particularly high long-term financial commitments.

Cost Impact Categories

Wage Replacement Escalation: Extended disability periods result in ongoing weekly benefit payments that can continue for months or years, representing the largest component of total claim costs.

Medical Cost Increases: Workers with extended opioid use require additional interventions including addiction treatment, alternative therapies, and extended rehabilitation services.

Vocational Rehabilitation Needs: Opioid-related complications require more intensive vocational services including job retraining, workplace modifications, and extended case management.

What solutions can reduce high-risk opioid prescribing?

Key solutions include comprehensive data collection across all states, targeted rural interventions, early detection systems for high-risk patterns within the first 3 months, cross-jurisdictional prescribing standards, and AI-powered medication risk assessment tools that flag dangerous prescribing patterns before they lead to long-term dependency.

Enhanced Data Collection

Implement comprehensive medication data collection systems in all states lacking detailed prescribing information. Victoria's model demonstrates the value of detailed medication monitoring.

Rural Area Interventions

Develop targeted interventions for rural and economically challenged areas showing higher rates of high-risk prescribing. Focus on prescriber education and alternative pain management access.

Early Detection Systems

Implement automated systems to identify high-risk prescribing patterns in the first three months when intervention can most effectively prevent long-term dependency.

AI-Powered Tools

Advanced medication risk assessment tools help claims managers identify potential high-risk patterns before they lead to dependency. Tools like the AllMeds Drug Interaction Checker instantly identify dangerous opioid combinations.

References

  1. HR Leader. (March 11, 2025). Monash University Study on Australian Opioid Prescribing in Workers Compensation
  2. Tefera, Y., Collie, A., et al. (2025). Healthy Working Lives Research Group. Monash University School of Public Health and Preventive Medicine
  3. Safe Work Australia. (2025). National Workers Compensation Statistics
  4. WorkSafe Victoria. (2025). Medication Prescribing Data Collection and Analysis