Corticosteroid | Low Risk

Tetracosactide (Synacthen Depot 1 mg/1 mL)

Tetracosactide risk profile, scheduling, and guidance for claims professionals and care workers . Also known as Synacthen Depot 1 mg/1 mL.

Source: PBS, TGA Updated April 2026

Tetracosactide (brand names: Synacthen Depot 1 mg/1 mL) is classified as Low risk (2 risk points) by AllMeds. It is a S4 medication under the TGA in Australia. ACTH analog causing corticosteroid effects with potential mood and cognitive impacts.

Key Takeaways

  • TGA Schedule: S4 in Australia
  • Risk level: Low (2 points)
  • Recommended maximum duration: 3 days
  • PBS listed: Subsidised under the Australian Pharmaceutical Benefits Scheme

Scheduling and Classification

Jurisdiction Classification Status
Australia (TGA) S4 PBS listed

Risk Profile

Risk Level Low
Risk Points 2
CNS Depressant No
Respiratory Risk No
Max Duration 3 days

ACTH analog causing corticosteroid effects with potential mood and cognitive impacts.

Regulatory and Compliance Guidance

When Tetracosactide appears on a claimant's medication list, claims professionals should assess whether the prescribing is appropriate for the compensable injury, whether the duration is within guidelines, and whether there are interactions with other medications on the claim.

Australia TGA / PBS / State Schemes

Classified as S4 under the Therapeutic Goods Administration (TGA).

Listed on the Pharmaceutical Benefits Scheme (PBS) for subsidised prescribing.

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Medical Disclaimer: This content is for informational purposes for claims professionals and care workers. It is not medical advice. Always consult a qualified healthcare professional for clinical decisions. Drug information is sourced from TGA, FDA, MHRA, PBS, NICE, and CDC databases and may not reflect the latest updates. AllMeds does not replace clinical judgement.