S2 | Pharmacy Medicine

What Schedule Is DIPHENHYDRAMINE HCL 25MG?

DIPHENHYDRAMINE HCL 25MG scheduling and classification across Australia, United States, and international jurisdictions. Also known as Allergy 36ct, Caseys 4good.

S2 in Australia Source: FDA Updated April 2026

DIPHENHYDRAMINE HCL 25MG (Allergy 36ct, Caseys 4good) is classified as S2 (Pharmacy Medicine - available from a pharmacy without a prescription, but must be provided by a pharmacist) under the Therapeutic Goods Administration (TGA) in Australia. It is FDA approved in the United States.

Key Takeaways

  • Australia (TGA): S2 - Pharmacy Medicine - available from a pharmacy without a prescription, but must be provided by a pharmacist
  • United States (FDA): Approved (Rx only)
  • Risk level: Low (2 points)

Scheduling by Jurisdiction

Jurisdiction Regulatory Body Classification Status
Australia TGA (Therapeutic Goods Administration) S2 Not PBS listed
United States FDA / DEA Rx only (not DEA scheduled) FDA approved

What S2 Means for DIPHENHYDRAMINE HCL 25MG

DIPHENHYDRAMINE HCL 25MG is classified as S2 under the TGA Standard for the Uniform Scheduling of Medicines and Poisons (SUSMP). Pharmacy Medicine - available from a pharmacy without a prescription, but must be provided by a pharmacist.

Claims and Workers Compensation Implications

When DIPHENHYDRAMINE HCL 25MG (S2) appears on a claimant's medication list, the scheduling classification affects how claims professionals should assess and manage the claim.

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Related Resources

Important: This page is general health information, not personal medical advice. If you have questions about your medication — including starting it, stopping it, changing the dose, or combining it with something else — speak with your doctor or pharmacist. For an emergency or suspected overdose, call your local emergency number or poison information service immediately. Information is drawn from regulator and clinical guideline sources (TGA, FDA, MHRA, NICE, PBS, CDC); see our methodology for details.