Other | Low Risk

Atovaquone + proguanil (AtovaquoPro Lupin 250/100)

What to know about Atovaquone + proguanil — also sold as AtovaquoPro Lupin 250/100, Malarone: uses, side effects, interactions, and safety considerations for people taking it or caring for someone who is.

Atovaquone + proguanil (brand names: AtovaquoPro Lupin 250/100, Malarone) is classified as Low risk (1 risk points) by AllMeds. It is a S4 medication under the TGA in Australia. Antimalarial combination with minimal impact on work capacity.

Key Takeaways

  • TGA Schedule: S4 in Australia
  • Risk level: Low (1 points)
  • Recommended maximum duration: 28 days
  • PBS listed: Subsidised under the Australian Pharmaceutical Benefits Scheme

Scheduling and Classification

Jurisdiction Classification Status
Australia (TGA) S4 PBS listed

Risk Profile

Risk Level Low
Risk Points 1
CNS Depressant No
Respiratory Risk No
Max Duration 28 days

Antimalarial combination with minimal impact on work capacity.

How Atovaquone + proguanil is regulated

Atovaquone + proguanil is overseen by medicines regulators in each country. The rules below explain how it's scheduled, what oversight applies, and what to discuss with your doctor or pharmacist before starting, changing, or stopping this medication.

Australia TGA / PBS / State Schemes

Classified as S4 under the Therapeutic Goods Administration (TGA).

Listed on the Pharmaceutical Benefits Scheme (PBS) for subsidised prescribing.

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Important: This page is general health information, not personal medical advice. If you have questions about your medication — including starting it, stopping it, changing the dose, or combining it with something else — speak with your doctor or pharmacist. For an emergency or suspected overdose, call your local emergency number or poison information service immediately. Information is drawn from regulator and clinical guideline sources (TGA, FDA, MHRA, NICE, PBS, CDC); see our methodology for details.