Bupropion (Zyban)
What to know about Bupropion — also sold as Zyban: uses, side effects, interactions, and safety considerations for people taking it or caring for someone who is.
Bupropion (brand names: Zyban) is classified as Low risk (2 risk points) by AllMeds. It is a S4 medication under the TGA in Australia. NDRI antidepressant with seizure risk at higher doses but minimal CNS depression.
Key Takeaways
- TGA Schedule: S4 in Australia
- Risk level: Low (2 points)
- PBS listed: Subsidised under the Australian Pharmaceutical Benefits Scheme
Scheduling and Classification
| Jurisdiction | Classification | Status |
|---|---|---|
| Australia (TGA) | S4 | PBS listed |
Risk Profile
NDRI antidepressant with seizure risk at higher doses but minimal CNS depression.
How Bupropion is regulated
Bupropion is overseen by medicines regulators in each country. The rules below explain how it's scheduled, what oversight applies, and what to discuss with your doctor or pharmacist before starting, changing, or stopping this medication.
Australia TGA / PBS / State Schemes
Classified as S4 under the Therapeutic Goods Administration (TGA).
Listed on the Pharmaceutical Benefits Scheme (PBS) for subsidised prescribing.
United Kingdom NICE / MHRA / FPM
NICE guidelines recommend certain antidepressants (amitriptyline, duloxetine) for chronic pain management. For personal injury claims, antidepressant prescribing should be assessed for injury relatedness.
Check this medication against your full medication list
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Important: This page is general health information, not personal medical advice. If you have questions about your medication — including starting it, stopping it, changing the dose, or combining it with something else — speak with your doctor or pharmacist. For an emergency or suspected overdose, call your local emergency number or poison information service immediately. Information is drawn from regulator and clinical guideline sources (TGA, FDA, MHRA, NICE, PBS, CDC); see our methodology for details.