Antidiabetic | Low Risk

Insulin degludec + insulin aspart (Ryzodeg Penfill)

What to know about Insulin degludec + insulin aspart — also sold as Ryzodeg Penfill: uses, side effects, interactions, and safety considerations for people taking it or caring for someone who is.

Insulin degludec + insulin aspart (brand names: Ryzodeg Penfill) is classified as Low risk (1 risk points) by AllMeds. It is a S4 medication under the TGA in Australia. Long-acting insulin combination with hypoglycemia risk requiring workplace safety consideration.

Key Takeaways

  • TGA Schedule: S4 in Australia
  • Risk level: Low (1 points)
  • PBS listed: Subsidised under the Australian Pharmaceutical Benefits Scheme

Scheduling and Classification

Jurisdiction Classification Status
Australia (TGA) S4 PBS listed

Risk Profile

Risk Level Low
Risk Points 1
CNS Depressant No
Respiratory Risk No

Long-acting insulin combination with hypoglycemia risk requiring workplace safety consideration.

How Insulin degludec + insulin aspart is regulated

Insulin degludec + insulin aspart is overseen by medicines regulators in each country. The rules below explain how it's scheduled, what oversight applies, and what to discuss with your doctor or pharmacist before starting, changing, or stopping this medication.

Australia TGA / PBS / State Schemes

Classified as S4 under the Therapeutic Goods Administration (TGA).

Listed on the Pharmaceutical Benefits Scheme (PBS) for subsidised prescribing.

Check this medication against your full medication list

Run a full risk assessment including Insulin degludec + insulin aspart interactions and compliance checks.

Allmeds AI Pharmacist scans interactions, schedules, and risk flags across your entire medication profile in minutes. Free for individuals; team plans for case managers, insurers, and schemes.

Important: This page is general health information, not personal medical advice. If you have questions about your medication — including starting it, stopping it, changing the dose, or combining it with something else — speak with your doctor or pharmacist. For an emergency or suspected overdose, call your local emergency number or poison information service immediately. Information is drawn from regulator and clinical guideline sources (TGA, FDA, MHRA, NICE, PBS, CDC); see our methodology for details.