Peptide | Low Risk

TB-500 (Thymosin Beta-4)

What to know about TB-500 (Thymosin Beta-4): uses, side effects, interactions, and safety considerations for people taking it or caring for someone who is.

TB-500 (Thymosin Beta-4) is classified as Low risk (2 risk points) by AllMeds. NOT TGA registered. Used via compounding for tissue repair. Banned by WADA. Limited human evidence.

Key Takeaways

  • Risk level: Low (2 points)

Scheduling and Classification

Jurisdiction Classification Status
Australia (TGA) Unscheduled Not PBS listed

Risk Profile

Risk Level Low
Risk Points 2
CNS Depressant No
Respiratory Risk No

NOT TGA registered. Used via compounding for tissue repair. Banned by WADA. Limited human evidence.

How TB-500 (Thymosin Beta-4) is regulated

TB-500 (Thymosin Beta-4) is overseen by medicines regulators in each country. The rules below explain how it's scheduled, what oversight applies, and what to discuss with your doctor or pharmacist before starting, changing, or stopping this medication.

Australia TGA / PBS / State Schemes

Classified as Unscheduled under the Therapeutic Goods Administration (TGA).

Clinical Evidence

  • Thymosin β4 and its role in tissue regeneration — review - Goldstein AL, et al. (2012)

    Review of thymosin beta-4 biology. Describes anti-inflammatory and tissue repair mechanisms. Mostly in vitro and animal models.

    Peer-reviewed but mostly preclinical data

  • WADA Prohibited List — TB-500/Thymosin Beta-4 - WADA (2024)

    Thymosin beta-4 and its synthetic analogues (TB-500) are prohibited under S2. Banned in and out of competition.

    International regulatory body

  • Huberman Lab: Peptides discussion including TB-500 - Andrew Huberman (2023)

    Discussed alongside BPC-157 as a tissue repair peptide. Notes systemic vs local effects.

    Popular science communicator, not a peptide researcher

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Important: This page is general health information, not personal medical advice. If you have questions about your medication — including starting it, stopping it, changing the dose, or combining it with something else — speak with your doctor or pharmacist. For an emergency or suspected overdose, call your local emergency number or poison information service immediately. Information is drawn from regulator and clinical guideline sources (TGA, FDA, MHRA, NICE, PBS, CDC); see our methodology for details.