zuclopenthixol decanoate (Clopixol Depot)
What to know about zuclopenthixol decanoate — also sold as Clopixol Depot: uses, side effects, interactions, and safety considerations for people taking it or caring for someone who is.
zuclopenthixol decanoate (brand names: Clopixol Depot) is classified as Moderate risk (4 risk points) by AllMeds. It is a S4 medication under the TGA in Australia. Long-acting depot antipsychotic with significant sedation, QTc prolongation risk, and extrapyramidal side effects affecting work capacity.
Key Takeaways
- TGA Schedule: S4 in Australia
- Risk level: Moderate (4 points)
- CNS depressant: May cause sedation, impair driving, and affect work capacity
- PBS listed: Subsidised under the Australian Pharmaceutical Benefits Scheme
Scheduling and Classification
| Jurisdiction | Classification | Status |
|---|---|---|
| Australia (TGA) | S4 | PBS listed |
Risk Profile
Long-acting depot antipsychotic with significant sedation, QTc prolongation risk, and extrapyramidal side effects affecting work capacity.
How zuclopenthixol decanoate is regulated
zuclopenthixol decanoate is overseen by medicines regulators in each country. The rules below explain how it's scheduled, what oversight applies, and what to discuss with your doctor or pharmacist before starting, changing, or stopping this medication.
Work capacity impact: As a CNS depressant, zuclopenthixol decanoate may impair driving, operating machinery, and cognitive function. Work capacity certificates should reflect any medication-related restrictions.
Australia TGA / PBS / State Schemes
Classified as S4 under the Therapeutic Goods Administration (TGA).
Listed on the Pharmaceutical Benefits Scheme (PBS) for subsidised prescribing.
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Important: This page is general health information, not personal medical advice. If you have questions about your medication — including starting it, stopping it, changing the dose, or combining it with something else — speak with your doctor or pharmacist. For an emergency or suspected overdose, call your local emergency number or poison information service immediately. Information is drawn from regulator and clinical guideline sources (TGA, FDA, MHRA, NICE, PBS, CDC); see our methodology for details.